Unexplained Infertility Treatment Malaysia
- Unexplained infertility is the diagnosis assigned when a clear cause for an individual’s or couple’s infertility cannot be determined through standard testing and clinical insights. It is a relatively common diagnosis, given in approximately 30% of infertility cases in Malaysia, as reproduction involves numerous individual factors.
- Despite the unknown exact cause, the information gathered about the individual patient(s) allows us to formulate infertility treatment options in Kuala Lumpur for achieving pregnancy success. These options may involve encouraging the couple or individual to persist with natural conception, following established guidelines for success, as well as utilizing treatments such as medications, intrauterine insemination (IUI), and in vitro fertilization (IVF).
What is Unexplained Infertility?
An unexplained infertility diagnosis is given when we can’t pinpoint a specific cause after our normal fertility testing protocols including a physical examination, discussion of sexual health background and conception practices. This diagnosis does not mean that there is no cause for the infertility. Rather, that the cause remains unknown despite current medical knowledge and testing.
Unexplained infertility is the diagnosis fertility specialists give after evaluation shows evidence of ovulation and unblocked fallopian tubes in the woman and healthy sperm production in the man. But our sophisticated diagnostic tools, coupled with the experience and insights of our doctor, can’t identify all possible abnormal situations in the couple’s reproductive systems.
The journal Fertility and Sterility reports that 30% of cases of infertility result in a diagnosis of unexplained infertility. While this is likely a particularly frustrating diagnosis for someone, it’s important to remember that a diagnosis (even this one) is the foundation for formulating a path to treatment.
We take that into consideration with this diagnosis and carefully explain the situation to the patient(s), including our suggestions on moving forward with treatments.
You’re Worth It, You’re Special
- Our patient coordinators and staff are proficient in two or three languages.
- We prioritize dedicating quality time and care to each individual.
- The fertility doctor personally attends to the patient during every visit.
- Perfect Fertility Center provides a boutique and highly personalized experience for our patients.
Potential Causes and Unexplained Infertility Diagnosis
Even following standard testing for both males and females, numerous unknown biological, environmental, and genetic variables may play a role in fertility. It is crucial to evaluate both partners. Some potential factors contributing to unexplained infertility may include:
Incorrect
Timing
This involves either not aligning intercourse with predicted ovulation or not engaging in sexual activity frequently enough
Genetic
Issues
Genetics can have subtle implications on fertility. For instance, a man might possess Y chromosome deletions or other genetic factors that could result in compromised fertility. Additionally, both the sperm and egg may exhibit chromosomal issues, hindering the process of fertilization.
Biologic
Issues
Abnormalities in a woman's ovaries, uterus, or fallopian tubes that may not be detected in standard testing could exist. Challenges might arise with releasing the egg before it matures, hormonal levels post-ovulation, cervical mucus, or the quality of the egg.
Unidentified Environmental Issues
The impact on fertility from exposure to specific chemicals, toxins, or pollutants might not be readily discernible through standard testing.
Infertility Testing Malaysia
We will review the medical history of both partners, including potential genetic issues within their families. Each partner will undergo a comprehensive physical examination.
Our specialists will perform a semen analysis for the male, assessing sperm count, movement, and morphology (shape). Hormone levels in the woman will be evaluated to determine if ovulation is occurring. A hysterosalpingogram examination will be conducted through the cervix to assess the uterus and fallopian tubes. Ultrasound may be utilized to examine for any uterine problems.
Our clinic offers advanced infertility treatment in Kuala Lumpur, ensuring a thorough evaluation and personalized care for each couple.
Arriving at this Diagnosis
To establish a diagnosis of unexplained infertility, our fertility specialist will have made the following determinations:
- No information gathered from discussions about the couple’s health history or their methods of attempting conception suggests a likely cause.
- The physical examination does not reveal any structural issues in the male, such as impediments to sperm delivery, or in the female, such as uterine fibroids.
- Analysis of the man’s semen shows no abnormalities.
- Testing confirms that at least one of the woman’s two fallopian tubes, where fertilization occurs, is open.
- The woman is ovulating regularly.
Unexplained Infertility Treatment
Given the numerous uncertainties associated with unexplained infertility, Dr. Marcus engages in discussions with patients, ensuring a comprehensive understanding of the diagnosis and the advantages and disadvantages of available treatment options. Drawing on his extensive experience, he recommends the most suitable treatment plan for the individual or couple.
We typically initiate treatment with less invasive options initially. It is often prudent to establish a time limit for each treatment protocol and transition to more advanced options if deemed necessary.
In essence, the treatment of unexplained infertility demands a personalized approach, considering the unique needs and circumstances of each individual.
Medications for ovulation stimulation
We might prescribe medications to the woman that influence reproductive hormones to enhance the production of healthier or more eggs during ovulation. These medications, including clomiphene citrate, letrozole, and gonadotropins, are administered in coordination with natural intercourse.
IUI for unexplained infertility
Intrauterine insemination (IUI) is endorsed by the American Society for Reproductive Medicine (ASRM) as the primary treatment for unexplained infertility, and it is frequently the preferred course of action in our treatment plans. IUI involves placing sperm obtained from the male into the woman's uterus through the cervix. It is a less invasive and more cost-effective option compared to in vitro fertilization (IVF).
IUI can be conducted during a natural ovulation cycle, typically when the woman releases a single egg. Alternatively, it can be paired with various medications aimed at enhancing the quantity or quality of eggs released during ovulation. In fact, this combined treatment approach is often the initial choice to explore.
IVF for unexplained infertility
In vitro fertilization (IVF) stands out as the most effective treatment for various causes of infertility, including unexplained cases. Typically, we recommend IVF after three unsuccessful rounds of intrauterine insemination (IUI). However, in collaboration with couples, we may opt for IVF as the initial treatment if the patients prefer a more expedited approach to achieve pregnancy, despite its more invasive and costly nature.
The American Society for Reproductive Medicine (ASRM) reports compelling evidence that for women aged 38 and older, initiating IVF yields higher pregnancy rates more rapidly than with IUI and ovulation stimulation. Additionally, ASRM highlights a lack of sufficient evidence to suggest that intracytoplasmic sperm injection (ICSI) with IVF enhances success rates in patients with unexplained infertility.
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